STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2Y2X9_CIOINUncharacterized protein. (137 aa)    
Predicted Functional Partners:
F6Q9A0_CIOIN
Uncharacterized protein.
 
     0.626
F6QXW9_CIOIN
Helicase ATP-binding domain-containing protein.
   
 
 0.570
F6UAB2_CIOIN
FANCM-MHF_bd domain-containing protein.
   
 
 0.570
H2XN42_CIOIN
Uncharacterized protein.
   
 
 0.570
F6RK68_CIOIN
Helicase ATP-binding domain-containing protein.
 
     0.554
LOC100181411
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 
 0.544
H2Y1I3_CIOIN
Uncharacterized protein.
  
 
 0.526
F6R213_CIOIN
Uncharacterized protein.
   
 0.517
LOC100185652
Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family.
   
 0.500
F6W282_CIOIN
DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.
  
  
 0.450
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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