STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C3XUS0_BRAFLHistone H3; Belongs to the histone H3 family. (136 aa)    
Predicted Functional Partners:
C3ZDP8_BRAFL
Uncharacterized protein.
   
 0.942
C3Z1B1_BRAFL
Uncharacterized protein.
   
 0.796
C3XQS8_BRAFL
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.733
C3Z789_BRAFL
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.732
C3ZYM4_BRAFL
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.732
C3XZY0_BRAFL
Histone H2A; Belongs to the histone H2A family.
   
 0.689
C3YLR8_BRAFL
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
   
 0.640
C3ZL20_BRAFL
Uncharacterized protein.
   
 0.637
C3YEA6_BRAFL
WW domain-containing protein.
   
 0.631
C3Z2G5_BRAFL
WD_REPEATS_REGION domain-containing protein.
    
 0.617
Your Current Organism:
Branchiostoma floridae
NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.