STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C3ZY94_BRAFLSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1889 aa)    
Predicted Functional Partners:
C3Y082_BRAFL
Uncharacterized protein.
   
 0.990
C3Z6V2_BRAFL
Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]
  
0.668
C3YYR7_BRAFL
GuKc domain-containing protein.
   
 0.610
C3ZQQ6_BRAFL
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
  
  
 
0.573
C3ZY97_BRAFL
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
  
  
 
0.556
C3YMT5_BRAFL
ANAPC4_WD40 domain-containing protein.
    
 0.551
C3ZY93_BRAFL
Ion_trans domain-containing protein.
  
  
 
0.551
C3ZY90_BRAFL
Ion_trans domain-containing protein.
  
  
 
0.548
C3XRQ5_BRAFL
Kringle domain-containing protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
     
 0.540
C3Y148_BRAFL
Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
     
  0.540
Your Current Organism:
Branchiostoma floridae
NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet
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