STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
S4R4A3_PETMATransmembrane protein 129, E3 ubiquitin protein ligase. (364 aa)    
Predicted Functional Partners:
S4RSM9_PETMA
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
 0.747
S4R6F6_PETMA
Peroxisomal biogenesis factor 6; Belongs to the AAA ATPase family.
   
  0.621
S4RJY1_PETMA
AAA domain-containing protein; Belongs to the AAA ATPase family.
   
 0.605
S4RTX4_PETMA
Protein YIPF.
    
  0.580
S4RDL3_PETMA
SLBP_RNA_bind domain-containing protein.
 
    
 0.574
S4REB6_PETMA
Protein YIPF.
    
  0.523
S4R8Y2_PETMA
Uncharacterized protein.
   
 0.522
S4RUF6_PETMA
AAA domain-containing protein; Belongs to the AAA ATPase family.
   
 0.522
S4RCT1_PETMA
Zmp:0000000662.
    
 
 0.405
S4RDJ3_PETMA
Uncharacterized protein.
   
  
 0.404
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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