Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
S4R4A3_PETMATransmembrane protein 129, E3 ubiquitin protein ligase. (364 aa)    
Predicted Functional Partners:
S4RSM9_PETMA
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
 0.969
S4RDL3_PETMA
SLBP_RNA_bind domain-containing protein.
 
    
 0.771
S4REJ7_PETMA
Coiled-coil domain containing 102A.
      
 0.769
S4RDJ3_PETMA
Uncharacterized protein.
      
 0.674
S4RVG7_PETMA
RBR-type E3 ubiquitin transferase.
      
 0.650
S4R7P4_PETMA
Family with sequence similarity 8 member A1b.
      
 0.626
S4RW93_PETMA
TACC_C domain-containing protein.
      
 0.610
S4R7Q4_PETMA
Bms1-type G domain-containing protein.
      
 0.604
S4RL77_PETMA
BMS1 ribosome biogenesis factor.
      
 0.604
S4RJY1_PETMA
AAA domain-containing protein; Belongs to the AAA ATPase family.
    
 0.595
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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