STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BCKDHA2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (405 aa)    
Predicted Functional Partners:
S4RUZ2_PETMA
2-oxoacid_dh domain-containing protein.
 
 0.996
DLST
Lipoyl-binding domain-containing protein.
  
 0.995
S4RLU2_PETMA
Dihydrolipoyl dehydrogenase.
 
 
 0.990
S4RKK1_PETMA
Thioredoxin reductase 3.
 
 
 0.988
S4R6I4_PETMA
Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.973
S4RX16_PETMA
Transketolase b.
  
 
 0.937
S4RQE6_PETMA
3-hydroxy-3-methylglutaryl-CoA lyase.
  
 
 0.936
S4RQV6_PETMA
Methylcrotonoyl-CoA carboxylase 2 (beta).
  
 
 0.934
S4RGS8_PETMA
Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.932
S4RXU5_PETMA
Citrate synthase; Belongs to the citrate synthase family.
    
 0.924
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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