Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
WDR1WD_REPEATS_REGION domain-containing protein. (613 aa)    
Predicted Functional Partners:
S4RX51_PETMA
Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family.
   
 
 0.947
S4RJQ7_PETMA
F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 
 0.857
S4RX81_PETMA
Uncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family.
    
   0.817
S4RH85_PETMA
Uncharacterized protein.
   
 0.816
ACTG2
Actin gamma 2, smooth muscle.
   
 0.816
ACTB
Beta-actin.
   
 0.816
S4R7F0_PETMA
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 
 0.813
S4RMX4_PETMA
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 
 0.813
S4RPS2_PETMA
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
 
 0.803
S4RTJ0_PETMA
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
 
 0.803
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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