Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
S4R4D8_PETMAMethionine sulfoxide reductase B1b. (472 aa)    
Predicted Functional Partners:
S4RDE2_PETMA
Helicase ATP-binding domain-containing protein.
    
 0.970
S4REK3_PETMA
Helicase ATP-binding domain-containing protein.
    
 0.970
FANCM
Uncharacterized protein.
    
 0.970
S4RTM7_PETMA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.920
MCM2
Minichromosome maintenance complex component 2.
   
 0.904
S4RDW5_PETMA
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
    
 0.900
S4RU69_PETMA
Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family.
   
 0.892
S4RVU6_PETMA
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
   
 0.891
S4RUH4_PETMA
Cell division cycle associated 7a.
    
 0.884
RAD51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
  
 0.879
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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