Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
S4R4E0_PETMAUncharacterized protein. (157 aa)    
Predicted Functional Partners:
GNB3-2
WD_REPEATS_REGION domain-containing protein.
   
 0.979
S4RWD0_PETMA
WD_REPEATS_REGION domain-containing protein.
   
 0.979
GNB5
Guanine nucleotide binding protein (G protein), beta 5b.
   
 0.979
PLCB1-2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
    
 0.970
GNG13
Guanine nucleotide binding protein (G protein), gamma 13b.
    
 0.966
S4RVY4_PETMA
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
 0.962
S4RPI4_PETMA
Uncharacterized protein.
 
   0.961
PRLHR2
Prolactin releasing hormone 2 receptor.
    
  0.952
TRHR2
Thyrotropin-releasing hormone receptor 2; Belongs to the G-protein coupled receptor 1 family.
    
  0.948
S4RM80_PETMA
Angiotensin II receptor, type 1a; Belongs to the G-protein coupled receptor 1 family.
    
 0.946
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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