Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
S4R4E7_PETMAUncharacterized protein. (683 aa)    
Predicted Functional Partners:
S4R697_PETMA
MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).
    
   0.919
SMARCAL1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.
      
 0.706
S4RZ60_PETMA
Zinc finger, RAN-binding domain containing 3.
      
 0.664
DNA2
DNA replication helicase/nuclease 2.
      
 0.650
RAD51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
      
 0.630
S4RRM4_PETMA
Exonuclease 1.
      
 0.620
S4RPK0_PETMA
Uncharacterized protein.
      
 0.616
S4RLM3_PETMA
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
      
 0.599
S4RV63_PETMA
Primase and polymerase (DNA-directed).
      
 0.486
S4RIL8_PETMA
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
      
 0.479
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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