Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PXNPaxillin. (226 aa)    
Predicted Functional Partners:
S4RUN4_PETMA
Protein tyrosine kinase 2ab.
    
 0.757
S4RF48_PETMA
Growth arrest-specific 7a.
    
 
 0.746
S4RC73_PETMA
Catenin (cadherin-associated protein), alpha 1.
   
 0.741
S4RP96_PETMA
Catenin (cadherin-associated protein), alpha-like 1.
   
 0.741
SUCLG1
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
 
      0.674
S4RWK1_PETMA
Uncharacterized protein.
 
      0.651
S4RVD8_PETMA
V-crk avian sarcoma virus CT10 oncogene homolog-like.
    
 0.641
S4RSN1_PETMA
Myosin, light chain 9a, regulatory.
   
 0.638
S4RHN3_PETMA
Uncharacterized protein.
 
      0.596
S4RLZ5_PETMA
Ribonucleotide reductase M2 polypeptide.
    
   0.570
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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