Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
S4R7D3_PETMADopamine receptor D2b; Belongs to the G-protein coupled receptor 1 family. (354 aa)    
Predicted Functional Partners:
S4RZD3_PETMA
Dopamine receptor D4b; Belongs to the G-protein coupled receptor 1 family.
    
0.993
GNB3-2
WD_REPEATS_REGION domain-containing protein.
    
  0.987
S4RWD0_PETMA
WD_REPEATS_REGION domain-containing protein.
    
  0.987
S4RGK6_PETMA
Uncharacterized protein.
    
 0.968
GNAO1
Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b.
    
 0.968
S4RZQ9_PETMA
Uncharacterized protein.
    
 0.968
S4S1R0_PETMA
Dopamine receptor D1b; Belongs to the G-protein coupled receptor 1 family.
  
0.963
GNB5
Guanine nucleotide binding protein (G protein), beta 5b.
    
 0.953
GNG13
Guanine nucleotide binding protein (G protein), gamma 13b.
    
  0.940
S4RVY4_PETMA
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
 0.939
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
Server load: low (20%) [HD]