Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
S4R7G3_PETMAAP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] (450 aa)    
Predicted Functional Partners:
S4RUY0_PETMA
AP complex subunit beta; Belongs to the adaptor complexes large subunit family.
   
 0.989
S4R6G9_PETMA
Transforming growth factor beta regulator 4.
    
 0.907
S4RFG4_PETMA
AP complex subunit beta.
    
 0.902
S4RWF4_PETMA
Uncharacterized protein.
   
 0.870
S4RS81_PETMA
NDK domain-containing protein; Belongs to the NDK family.
    
 0.840
S4R4N9_PETMA
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
    
 0.819
S4RMK2_PETMA
Uncharacterized protein.
    
 
 0.775
S4RVX9_PETMA
WD repeat domain 90.
    
 
 0.775
AP3B2
AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.
     
 0.739
S4RVM3_PETMA
HEAT repeat containing 5B.
    
 
 0.733
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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