Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
S4R7Q2_PETMAB30.2/SPRY domain-containing protein. (154 aa)    
Predicted Functional Partners:
S4RF48_PETMA
Growth arrest-specific 7a.
    
  0.491
CRYGS-3
Crystallin gamma S; Belongs to the beta/gamma-crystallin family.
  
     0.468
S4RTC7_PETMA
Uncharacterized protein.
    
 0.424
UBB
Ubiquitin B.
    
  0.410
UBE2N
Ubiquitin conjugating enzyme E2 N.
    
 0.406
S4RAY0_PETMA
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
  0.400
ENSPMAP00000002379
annotation not available
    
  0.400
ENSPMAP00000002380
annotation not available
    
  0.400
ENSPMAP00000002382
annotation not available
    
  0.400
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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