Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
FGGFibrinogen gamma chain; Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. (333 aa)    
Predicted Functional Partners:
FIBB_PETMA
Fibrinogen beta chain; Fibrinogen has a double function: yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation.
   
0.999
FIBA1_PETMA
Fibrinogen alpha-1 chain; Fibrinogen has a double function: yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation.
 
 
 0.999
FIBA2_PETMA
Fibrinogen alpha-2 chain; Fibrinogen has a double function: yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation.
   
0.998
S4REY0_PETMA
Uncharacterized protein; Belongs to the peptidase S1 family. Plasminogen subfamily.
   
 0.997
S4R938_PETMA
Uncharacterized protein.
   
 0.949
S4RUS7_PETMA
Serpin peptidase inhibitor, clade D (heparin cofactor), member 1; Belongs to the serpin family.
   
 0.889
S4RY75_PETMA
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 0.832
S4RGF5_PETMA
Asporin; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
    
 
 0.805
S4RC14_PETMA
Fibronectin 1a.
   
 0.773
S4RSM3_PETMA
Integrin beta; Belongs to the integrin beta chain family.
    
 0.753
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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