Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (875 aa)    
Predicted Functional Partners:
S4RJB6_PETMA
Polymerase (RNA) II (DNA directed) polypeptide C.
  
 0.999
S4RV21_PETMA
DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.
   
 0.999
S4RJW7_PETMA
RPOL4c domain-containing protein.
    
 0.998
S4RR50_PETMA
Transcription elongation factor SPT5.
   
 0.978
GTF2F2
General transcription factor IIF subunit 2.
    
 0.972
S4RAQ1_PETMA
RNA_pol_Rpb2_1 domain-containing protein.
 
 
 
 0.971
S4RUR2_PETMA
Uncharacterized protein; Belongs to the universal ribosomal protein uS11 family.
  
 
 0.963
S4RW63_PETMA
Uncharacterized protein.
   
 0.961
S4RLA2_PETMA
RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.
   
 0.959
S4RR79_PETMA
Integrator complex subunit 5.
    
 0.956
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.