Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
S4R804_PETMAUncharacterized protein. (481 aa)    
Predicted Functional Partners:
S4R9J7_PETMA
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.973
S4R953_PETMA
Ubiquitin-conjugating enzyme E2Ia; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.932
S4RLI2_PETMA
Uncharacterized protein.
  
  
 
0.901
S4RTM7_PETMA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 
 0.894
S4RKW4_PETMA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
   
 
 0.885
S4RNH8_PETMA
SP-RING-type domain-containing protein.
    
 
 0.859
S4RCZ6_PETMA
ULP_PROTEASE domain-containing protein.
   
 
 0.848
S4R517_PETMA
Signal transducer and activator of transcription.
    
 0.836
S4RQ37_PETMA
Uncharacterized protein.
    
 0.836
S4RXL5_PETMA
Signal transducer and activator of transcription.
    
 0.836
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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