Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
S4R882_PETMATBC1 domain family, member 5. (663 aa)    
Predicted Functional Partners:
S4R4P9_PETMA
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 
 0.992
S4RCJ6_PETMA
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
    
 
 0.990
S4RKW0_PETMA
VPS26, retromer complex component A.
   
 
 0.989
S4RIU7_PETMA
RAB36, member RAS oncogene family.
   
 
 0.925
S4RHC0_PETMA
Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.
    
 
 0.924
S4REL7_PETMA
Sorting nexin 1a.
    
 
 0.840
S4RYY1_PETMA
Sorting nexin 17.
    
 
 0.773
S4RAT5_PETMA
Sorting nexin 3.
    
 
 0.748
SNX31
Sorting nexin 31.
    
 
 0.697
S4S036_PETMA
ER membrane protein complex subunit 3; Belongs to the EMC3 family.
      
 0.686
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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