XPO1 protein (Petromyzon marinus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

XPO1

Importin N-terminal domain-containing protein. (1072 aa)

Predicted Functional Partners:

S4RVS2_PETMA

0.993

S4RBB2_PETMA

0.985

S4REY2_PETMA

0.979

S4RKC1_PETMA

0.959

S4RQ53_PETMA

0.955

XPO5

0.951

S4RHF3_PETMA

0.936

RANBP2

0.936

S4RH17_PETMA

0.928

S4RW40_PETMA

0.928

Your Current Organism:

Petromyzon marinus

NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RANBP2	S4RBB2_PETMA	ENSPMAP00000007926	ENSPMAP00000002493	RAN binding protein 2.	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.931
RANBP2	S4RH17_PETMA	ENSPMAP00000007926	ENSPMAP00000004499	RAN binding protein 2.	Uncharacterized protein.	0.969
RANBP2	S4RHF3_PETMA	ENSPMAP00000007926	ENSPMAP00000004635	RAN binding protein 2.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.979
RANBP2	S4RKC1_PETMA	ENSPMAP00000007926	ENSPMAP00000005654	RAN binding protein 2.	Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family.	0.777
RANBP2	S4RQ53_PETMA	ENSPMAP00000007926	ENSPMAP00000007339	RAN binding protein 2.	Uncharacterized protein.	0.483
RANBP2	S4RVS2_PETMA	ENSPMAP00000007926	ENSPMAP00000009312	RAN binding protein 2.	CSE1 chromosome segregation 1-like (yeast).	0.821
RANBP2	S4RW40_PETMA	ENSPMAP00000007926	ENSPMAP00000009430	RAN binding protein 2.	Nup214_FG domain-containing protein.	0.969
RANBP2	XPO1	ENSPMAP00000007926	ENSPMAP00000001414	RAN binding protein 2.	Importin N-terminal domain-containing protein.	0.936
RANBP2	XPO5	ENSPMAP00000007926	ENSPMAP00000006072	RAN binding protein 2.	Exportin 5.	0.936
S4RBB2_PETMA	RANBP2	ENSPMAP00000002493	ENSPMAP00000007926	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	RAN binding protein 2.	0.931
S4RBB2_PETMA	S4REY2_PETMA	ENSPMAP00000002493	ENSPMAP00000003764	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Exportin 7.	0.400
S4RBB2_PETMA	S4RH17_PETMA	ENSPMAP00000002493	ENSPMAP00000004499	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Uncharacterized protein.	0.707
S4RBB2_PETMA	S4RHF3_PETMA	ENSPMAP00000002493	ENSPMAP00000004635	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.931
S4RBB2_PETMA	S4RKC1_PETMA	ENSPMAP00000002493	ENSPMAP00000005654	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family.	0.906
S4RBB2_PETMA	S4RQ53_PETMA	ENSPMAP00000002493	ENSPMAP00000007339	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Uncharacterized protein.	0.705
S4RBB2_PETMA	S4RVS2_PETMA	ENSPMAP00000002493	ENSPMAP00000009312	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	CSE1 chromosome segregation 1-like (yeast).	0.869
S4RBB2_PETMA	S4RW40_PETMA	ENSPMAP00000002493	ENSPMAP00000009430	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Nup214_FG domain-containing protein.	0.707
S4RBB2_PETMA	XPO1	ENSPMAP00000002493	ENSPMAP00000001414	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Importin N-terminal domain-containing protein.	0.985
S4RBB2_PETMA	XPO5	ENSPMAP00000002493	ENSPMAP00000006072	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Exportin 5.	0.950
S4REY2_PETMA	S4RBB2_PETMA	ENSPMAP00000003764	ENSPMAP00000002493	Exportin 7.	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.400