| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MCM2 | MCM7 | ENSPMAP00000005297 | ENSPMAP00000005986 | Minichromosome maintenance complex component 2. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.999 |
| MCM2 | S4R893_PETMA | ENSPMAP00000005297 | ENSPMAP00000001424 | Minichromosome maintenance complex component 2. | Origin recognition complex, subunit 3. | 0.998 |
| MCM2 | S4RAX6_PETMA | ENSPMAP00000005297 | ENSPMAP00000002357 | Minichromosome maintenance complex component 2. | Minichromosome maintenance complex component 5; Belongs to the MCM family. | 0.999 |
| MCM2 | S4RKL0_PETMA | ENSPMAP00000005297 | ENSPMAP00000005743 | Minichromosome maintenance complex component 2. | DNA helicase; Belongs to the MCM family. | 0.999 |
| MCM2 | S4RP55_PETMA | ENSPMAP00000005297 | ENSPMAP00000006991 | Minichromosome maintenance complex component 2. | Histone acetyltransferase 1. | 0.474 |
| MCM2 | S4RSD9_PETMA | ENSPMAP00000005297 | ENSPMAP00000008128 | Minichromosome maintenance complex component 2. | MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like; Belongs to the MCM family. | 0.999 |
| MCM2 | S4RVW2_PETMA | ENSPMAP00000005297 | ENSPMAP00000009352 | Minichromosome maintenance complex component 2. | Minichromosome maintenance 10 replication initiation factor. | 0.996 |
| MCM2 | S4RW95_PETMA | ENSPMAP00000005297 | ENSPMAP00000009485 | Minichromosome maintenance complex component 2. | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | 0.999 |
| MCM2 | S4RWL2_PETMA | ENSPMAP00000005297 | ENSPMAP00000009602 | Minichromosome maintenance complex component 2. | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.999 |
| MCM2 | S4RXB0_PETMA | ENSPMAP00000005297 | ENSPMAP00000009850 | Minichromosome maintenance complex component 2. | Origin recognition complex, subunit 2. | 0.999 |
| MCM7 | MCM2 | ENSPMAP00000005986 | ENSPMAP00000005297 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Minichromosome maintenance complex component 2. | 0.999 |
| MCM7 | S4R893_PETMA | ENSPMAP00000005986 | ENSPMAP00000001424 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex, subunit 3. | 0.993 |
| MCM7 | S4RAX6_PETMA | ENSPMAP00000005986 | ENSPMAP00000002357 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Minichromosome maintenance complex component 5; Belongs to the MCM family. | 0.999 |
| MCM7 | S4RKL0_PETMA | ENSPMAP00000005986 | ENSPMAP00000005743 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
| MCM7 | S4RSD9_PETMA | ENSPMAP00000005986 | ENSPMAP00000008128 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like; Belongs to the MCM family. | 0.999 |
| MCM7 | S4RVW2_PETMA | ENSPMAP00000005986 | ENSPMAP00000009352 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Minichromosome maintenance 10 replication initiation factor. | 0.999 |
| MCM7 | S4RW95_PETMA | ENSPMAP00000005986 | ENSPMAP00000009485 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | 0.995 |
| MCM7 | S4RWL2_PETMA | ENSPMAP00000005986 | ENSPMAP00000009602 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.999 |
| MCM7 | S4RXB0_PETMA | ENSPMAP00000005986 | ENSPMAP00000009850 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex, subunit 2. | 0.998 |
| S4R893_PETMA | MCM2 | ENSPMAP00000001424 | ENSPMAP00000005297 | Origin recognition complex, subunit 3. | Minichromosome maintenance complex component 2. | 0.998 |