Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
S4R897_PETMAMyosin IEa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1119 aa)    
Predicted Functional Partners:
S4R484_PETMA
Osteoclast stimulating factor 1.
    
  0.854
S4RSH4_PETMA
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 
 0.825
S4RZG1_PETMA
TH1 domain-containing protein.
 
 
    0.823
S4R6X1_PETMA
Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.
    
 
 0.815
S4RL25_PETMA
Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
    
 
 0.795
S4RMB1_PETMA
TH1 domain-containing protein.
 
 
    0.793
S4R9V6_PETMA
F-BAR domain-containing protein.
   
 
 0.741
S4RPW9_PETMA
Thyroid hormone receptor interactor 10b.
   
 
 0.741
S4R7T0_PETMA
WH2 domain-containing protein.
   
 
 0.714
S4RFJ4_PETMA
WASP like actin nucleation promoting factor.
   
 
 0.714
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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