Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PXN-2Paxillin. (555 aa)    
Predicted Functional Partners:
S4RUN4_PETMA
Protein tyrosine kinase 2ab.
    
 0.994
S4RVD8_PETMA
V-crk avian sarcoma virus CT10 oncogene homolog-like.
    
 0.986
S4RUM8_PETMA
Protein kinase domain-containing protein.
   
 0.982
S4RKT8_PETMA
Protein kinase domain-containing protein.
    
 0.966
S4RC00_PETMA
Uncharacterized protein.
    
 0.932
PARVA
Parvin, alpha b.
    
 0.932
PARVA-2
Parvin, beta.
    
 0.932
S4RSN1_PETMA
Myosin, light chain 9a, regulatory.
   
 0.921
S4RSM3_PETMA
Integrin beta; Belongs to the integrin beta chain family.
    
 0.916
GIT2
GIT ArfGAP 2.
    
 
 0.876
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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