Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
S4R8H1_PETMAUncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (199 aa)    
Predicted Functional Partners:
S4RBH4_PETMA
MIF4G domain-containing protein.
   
 0.999
S4RJP6_PETMA
MAPK interacting serine/threonine kinase 1.
    
 0.985
S4RKP9_PETMA
MAPK interacting serine/threonine kinase 2a; Belongs to the protein kinase superfamily.
    
 0.985
S4RDU8_PETMA
Eukaryotic translation initiation factor 4, gamma 2a.
   
 0.984
NCBP1
Nuclear cap binding protein subunit 1.
    
 0.978
S4RD25_PETMA
Poly(A) binding protein, cytoplasmic 4 (inducible form).
   
 0.976
S4RU06_PETMA
Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.
   
 0.976
EIF3B
Eukaryotic translation initiation factor 3 subunit B; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
   
 
 0.973
S4RRR6_PETMA
DEAD (Asp-Glu-Ala-Asp) box helicase 6; Belongs to the DEAD box helicase family.
   
 0.964
S4RSN8_PETMA
40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.
   
 
 0.960
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
Server load: low (28%) [HD]