Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
S4R8K1_PETMATHUMP domain containing 1. (263 aa)    
Predicted Functional Partners:
NAT10
RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
   
 0.986
DUS2
Dihydrouridine synthase 2.
   
 
 0.901
S4RHT4_PETMA
tRNA (guanine(26)-N(2))-dimethyltransferase.
   
 
 0.852
S4RMN3_PETMA
tRNA (guanine(26)-N(2))-dimethyltransferase.
   
 
 0.852
S4RNV6_PETMA
Pseudouridine synthase 7 like.
   
 
 0.736
S4RIQ6_PETMA
Pseudouridine synthase 1.
   
 
 0.714
OXT
Arginine vasopressin; Belongs to the vasopressin/oxytocin family.
      
 0.639
S4RZ96_PETMA
Transmembrane protein 183A.
      
 0.613
S4R896_PETMA
THUMP domain containing 3.
    
   0.597
TINAGL1
Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.
      
 0.589
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
Server load: low (14%) [HD]