Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
S4R8K6_PETMAAconitase 1, soluble; Belongs to the aconitase/IPM isomerase family. (894 aa)    
Predicted Functional Partners:
S4R485_PETMA
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.998
S4RXU5_PETMA
Citrate synthase; Belongs to the citrate synthase family.
  
 0.998
S4RE81_PETMA
Isocitrate dehydrogenase (NAD(+)) 3 gamma.
  
 0.989
S4RA83_PETMA
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.987
ACLY
ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
  
 0.978
ACLY-2
ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
  
 0.978
S4RK47_PETMA
F-box and leucine-rich repeat protein 5.
    
 0.963
S4R5Z6_PETMA
SUMO peptidase family member, NEDD8 specific.
  
 
 0.933
S4RB24_PETMA
Aconitase 1, soluble; Belongs to the aconitase/IPM isomerase family.
  
  
 
0.901
SUCLG1
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
  
 0.887
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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