Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
S4R8K9_PETMAHDAC_interact domain-containing protein. (1299 aa)    
Predicted Functional Partners:
S4RXT2_PETMA
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 0.997
S4RTP1_PETMA
MBD domain-containing protein.
    
 0.991
S4RV40_PETMA
Hist_deacetyl domain-containing protein.
   
 0.988
S4R6P2_PETMA
SANT domain-containing protein.
    
 0.983
S4RM85_PETMA
ARID domain-containing protein.
   
 0.982
S4RN39_PETMA
AT rich interactive domain 4A (RBP1-like).
   
 0.982
SAP30
Sin3A associated protein 30.
    
 0.976
PHF12
PHD finger protein 12.
   
 
 0.972
S4RRX9_PETMA
Retinoblastoma binding protein 4, like.
    
 0.971
S4RRA4_PETMA
Mortality factor 4 like 1.
   
 0.970
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.