Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
S4R8N0_PETMASterol regulatory element binding transcription factor 2. (1069 aa)    
Predicted Functional Partners:
S4RQ06_PETMA
Uncharacterized protein.
    
 0.974
S4RRQ0_PETMA
Karyopherin (importin) beta 1.
    
 0.924
MED15
Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 
 0.911
S4RJD3_PETMA
E1A binding protein p300 a.
    
 0.899
S4RG30_PETMA
Peptidase_M50 domain-containing protein.
    
 0.888
S4R9F8_PETMA
Membrane-bound transcription factor peptidase, site 1.
    
 0.824
S4R5M7_PETMA
Coiled-coil domain containing 57.
   
 0.822
S4RDZ4_PETMA
Niemann-Pick disease, type C1.
    
 0.819
NPC1L1
SSD domain-containing protein.
    
 0.819
HMGCR
3-hydroxy-3-methylglutaryl coenzyme A reductase.
   
 0.811
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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