STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
S4R8U4_PETMAGeneral transcription factor IIH, polypeptide 2. (253 aa)    
Predicted Functional Partners:
S4RAA5_PETMA
MNAT1 component of CDK activating kinase.
   
 0.999
S4RIB7_PETMA
General transcription factor IIH, polypeptide 3.
   
 0.999
S4RQB2_PETMA
Excision repair cross-complementation group 2.
    
 0.999
S4REK9_PETMA
Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
   
 0.998
S4RK75_PETMA
Excision repair cross-complementation group 3.
    
 0.998
S4RLL9_PETMA
General transcription factor IIE, polypeptide 1, alpha.
   
 0.997
S4R5M3_PETMA
Cyclin_C_2 domain-containing protein.
   
 0.991
S4RI17_PETMA
General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
   
 0.990
S4RSV8_PETMA
General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
   
 0.990
S4RJB6_PETMA
Polymerase (RNA) II (DNA directed) polypeptide C.
   
 0.987
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.