S4R8V4_PETMA protein (Petromyzon marinus) - STRING interaction network

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S4R8V4_PETMA

Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (306 aa)

Predicted Functional Partners:

S4RHA6_PETMA

0.621

S4RHW3_PETMA

0.621

S4RHX2_PETMA

0.621

S4RJB8_PETMA

0.621

S4RTC2_PETMA

0.621

S4RWD5_PETMA

0.621

S4R6G0_PETMA

0.478

S4RIR1_PETMA

0.460

S4RS67_PETMA

0.444

SMARCAL1

0.432

Your Current Organism:

Petromyzon marinus

NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
S4R6G0_PETMA	S4R8V4_PETMA	ENSPMAP00000000790	ENSPMAP00000001635	SprT-like domain-containing protein.	Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...]	0.478
S4R8V4_PETMA	S4R6G0_PETMA	ENSPMAP00000001635	ENSPMAP00000000790	Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...]	SprT-like domain-containing protein.	0.478
S4R8V4_PETMA	S4RHA6_PETMA	ENSPMAP00000001635	ENSPMAP00000004588	Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...]	Uncharacterized protein.	0.621
S4R8V4_PETMA	S4RHW3_PETMA	ENSPMAP00000001635	ENSPMAP00000004795	Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...]	Uncharacterized protein.	0.621
S4R8V4_PETMA	S4RHX2_PETMA	ENSPMAP00000001635	ENSPMAP00000004804	Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...]	Uncharacterized protein.	0.621
S4R8V4_PETMA	S4RIR1_PETMA	ENSPMAP00000001635	ENSPMAP00000005093	Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...]	Ligase IV, DNA, ATP-dependent; Belongs to the ATP-dependent DNA ligase family.	0.460
S4R8V4_PETMA	S4RJB8_PETMA	ENSPMAP00000001635	ENSPMAP00000005300	Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...]	Hydin_ADK domain-containing protein.	0.621
S4R8V4_PETMA	S4RS67_PETMA	ENSPMAP00000001635	ENSPMAP00000008056	Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...]	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	0.444
S4R8V4_PETMA	S4RTC2_PETMA	ENSPMAP00000001635	ENSPMAP00000008462	Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...]	Adenylate kinase 5, like; Belongs to the adenylate kinase family.	0.621
S4R8V4_PETMA	S4RWD5_PETMA	ENSPMAP00000001635	ENSPMAP00000009525	Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...]	Adenylate kinase 2; Belongs to the adenylate kinase family.	0.621
S4R8V4_PETMA	SMARCAL1	ENSPMAP00000001635	ENSPMAP00000000003	Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...]	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.	0.432
S4RHA6_PETMA	S4R8V4_PETMA	ENSPMAP00000004588	ENSPMAP00000001635	Uncharacterized protein.	Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...]	0.621
S4RHA6_PETMA	S4RHW3_PETMA	ENSPMAP00000004588	ENSPMAP00000004795	Uncharacterized protein.	Uncharacterized protein.	0.861
S4RHA6_PETMA	S4RHX2_PETMA	ENSPMAP00000004588	ENSPMAP00000004804	Uncharacterized protein.	Uncharacterized protein.	0.923
S4RHA6_PETMA	S4RTC2_PETMA	ENSPMAP00000004588	ENSPMAP00000008462	Uncharacterized protein.	Adenylate kinase 5, like; Belongs to the adenylate kinase family.	0.884
S4RHA6_PETMA	S4RWD5_PETMA	ENSPMAP00000004588	ENSPMAP00000009525	Uncharacterized protein.	Adenylate kinase 2; Belongs to the adenylate kinase family.	0.803
S4RHW3_PETMA	S4R8V4_PETMA	ENSPMAP00000004795	ENSPMAP00000001635	Uncharacterized protein.	Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...]	0.621
S4RHW3_PETMA	S4RHA6_PETMA	ENSPMAP00000004795	ENSPMAP00000004588	Uncharacterized protein.	Uncharacterized protein.	0.861
S4RHW3_PETMA	S4RHX2_PETMA	ENSPMAP00000004795	ENSPMAP00000004804	Uncharacterized protein.	Uncharacterized protein.	0.999
S4RHW3_PETMA	S4RJB8_PETMA	ENSPMAP00000004795	ENSPMAP00000005300	Uncharacterized protein.	Hydin_ADK domain-containing protein.	0.861

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