Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EPB41L2FERM domain-containing protein. (608 aa)    
Predicted Functional Partners:
S4S087_PETMA
4_1_CTD domain-containing protein.
 
      0.899
S4RAE9_PETMA
Uncharacterized protein.
 
    
 0.667
S4RTA4_PETMA
Membrane palmitoylated protein 2; Belongs to the MAGUK family.
    
 0.612
EIF3A
Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
    
   0.586
S4RHJ8_PETMA
Membrane palmitoylated protein 2; Belongs to the MAGUK family.
    
 0.583
S4RND2_PETMA
Calcium/calmodulin-dependent protein kinase II alpha.
   
 0.467
S4RU19_PETMA
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.467
S4RRP9_PETMA
COesterase domain-containing protein.
    
  0.428
S4RYI7_PETMA
COesterase domain-containing protein.
    
  0.428
S4RKC5_PETMA
Cyclic nucleotide-binding domain-containing protein.
      
 0.419
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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