Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
S4R901_PETMACasein kinase 1, alpha 1; Belongs to the protein kinase superfamily. (198 aa)    
Predicted Functional Partners:
S4RE68_PETMA
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.990
CTNNB1
Catenin beta 1.
   
 0.988
CTNNB1-2
Catenin beta 1.
   
 0.988
CTNNB1-3
Catenin beta 1.
   
 0.988
CTNNB1-4
Catenin beta 1.
   
 0.988
S4RKD3_PETMA
RGS domain-containing protein.
    
 0.987
S4RNQ4_PETMA
RGS domain-containing protein.
    
 0.987
S4RT66_PETMA
DIX domain-containing protein.
    
 0.987
S4RXK8_PETMA
RGS domain-containing protein.
    
 0.987
S4RZB8_PETMA
Uncharacterized protein.
    
 0.960
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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