Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISG20Interferon stimulated exonuclease gene 20. (184 aa)    
Predicted Functional Partners:
S4RDD2_PETMA
RRM domain-containing protein.
   
   0.847
S4R5Y2_PETMA
Helicase C-terminal domain-containing protein.
  
 0.830
S4RH56_PETMA
Uncharacterized protein.
   
 
 0.771
S4RTM7_PETMA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.761
S4RF70_PETMA
Angio-associated, migratory cell protein.
   
   0.757
S4RWR0_PETMA
Ribosomal protein L8.
   
  0.736
S4RU29_PETMA
NOP58 ribonucleoprotein homolog (yeast).
   
 
 0.730
PAN3
PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...]
    
 0.721
S4RSR7_PETMA
RNA helicase.
  
 0.698
S4RA80_PETMA
GMPS ATP-PPase domain-containing protein.
  
 
 0.697
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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