Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (908 aa)    
Predicted Functional Partners:
S4R6J6_PETMA
MYD88 innate immune signal transduction adaptor.
    
 0.968
S4RMR7_PETMA
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.913
S4R4V7_PETMA
Interleukin-1 receptor-associated kinase 4.
    
 0.819
S4RFF2_PETMA
Inhibitor of nuclear factor kappa B kinase subunit epsilon.
   
 0.773
UNC93B1
Unc-93 homolog B1, TLR signaling regulator.
    
 0.764
S4R4E5_PETMA
TNF receptor-associated factor.
   
 0.759
S4RSA6_PETMA
Uncharacterized protein.
   
 
 0.701
S4R701_PETMA
Uncharacterized protein.
    
 0.697
S4RT09_PETMA
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.693
S4R516_PETMA
Myxovirus (influenza) resistance B; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
   
 0.645
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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