Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IP6K2Kinase; Belongs to the inositol phosphokinase (IPK) family. (424 aa)    
Predicted Functional Partners:
S4RMM5_PETMA
RimK domain-containing protein.
    
 0.967
S4RTQ5_PETMA
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...]
    
 0.967
IP6K2-2
Kinase; Belongs to the inositol phosphokinase (IPK) family.
  
  
 
0.901
UBXN4
UBX domain protein 4.
    
   0.676
S4RLQ8_PETMA
ANK_REP_REGION domain-containing protein.
    
 0.652
NUDT3
Nudix (nucleoside diphosphate linked moiety X)-type motif 3a.
    
 
 0.597
S4RSB4_PETMA
Zinc finger, AN1-type domain 2A.
      
 0.567
S4RD21_PETMA
Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
     
 0.564
S4RWM6_PETMA
Testis expressed 11.
      
 0.555
S4S199_PETMA
Fem-1 homolog c (C. elegans).
    
 0.531
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.