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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SUCLG1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (324 aa)    
Predicted Functional Partners:
SUCLA2
ATP-grasp domain-containing protein.
 0.999
S4REZ7_PETMA
Succinate-CoA ligase, GDP-forming, beta subunit.
 
 0.999
S4RY63_PETMA
Oxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide).
 
 0.995
S4RUZ2_PETMA
2-oxoacid_dh domain-containing protein.
 
 0.992
S4RI84_PETMA
Dehydrogenase E1 and transketolase domain containing 1.
 
 0.991
DLST
Lipoyl-binding domain-containing protein.
  
 0.990
ACLY
ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
  
0.990
ACLY-2
ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
  
0.990
S4RXU5_PETMA
Citrate synthase; Belongs to the citrate synthase family.
  
 0.986
S4RKF9_PETMA
Succinate dehydrogenase complex, subunit A, flavoprotein (Fp).
 
 0.981
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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