Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
INPP1Inositol polyphosphate-1-phosphatase. (387 aa)    
Predicted Functional Partners:
S4RGH0_PETMA
Inositol monophosphatase 1.
    
 0.977
PLCB1-2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
    
 0.910
S4RC86_PETMA
Inositol monophosphatase domain containing 1.
     
 0.902
ITPK1
Inositol-tetrakisphosphate 1-kinase; Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Belongs to the ITPK1 family.
     
 0.901
ITPK1-2
Inositol-tetrakisphosphate 1-kinase; Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Belongs to the ITPK1 family.
     
 0.901
S4RA52_PETMA
Phosphoinositide phospholipase C.
     
  0.900
S4RGN7_PETMA
Phosphoinositide phospholipase C.
     
  0.900
PLCD4
Phosphoinositide phospholipase C.
     
  0.900
ISYNA1
Inositol-3-phosphate synthase 1.
     
 0.782
S4RRN9_PETMA
Protein kinase domain-containing protein.
      
 0.652
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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