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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
S4R9T4_PETMA3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (258 aa)    
Predicted Functional Partners:
S4RRT7_PETMA
Steroid 5 alpha-reductase 3.
     
0.856
S4R558_PETMA
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.819
S4RRW7_PETMA
Cytochrome P450, family 17, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family.
     
 0.815
S4RW13_PETMA
Hydroxysteroid (17-beta) dehydrogenase 12b; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.808
S4RES3_PETMA
3Beta_HSD domain-containing protein.
     
 0.803
SLC34A3
Solute carrier family 34 member 3.
     
 0.800
S4RFL6_PETMA
Si:ch73-334d15.1; Belongs to the UDP-glycosyltransferase family.
     
 0.791
S4RT56_PETMA
3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family.
     
 0.719
S4RHJ2_PETMA
Aldo_ket_red domain-containing protein.
   
 
 0.715
S4RRZ6_PETMA
Aldo_ket_red domain-containing protein.
   
 
 0.715
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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