Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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Score
S4R9T4_PETMA3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (258 aa)    
Predicted Functional Partners:
S4RRT7_PETMA
Steroid 5 alpha-reductase 3.
     
0.959
S4RRW7_PETMA
Cytochrome P450, family 17, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family.
     
 0.940
S4RTG0_PETMA
S5A_REDUCTASE domain-containing protein.
  
  
 
0.905
UGT1A1
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
     
 0.901
S4RU50_PETMA
Uncharacterized protein.
     
 0.901
S4RUT3_PETMA
Uncharacterized protein.
     
 0.901
UGT1A1-2
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
     
 0.901
S4RBR6_PETMA
Aldedh domain-containing protein.
      
 0.543
S4RP44_PETMA
Ubiquitin-like domain-containing protein.
 
      0.522
S4RJ83_PETMA
Tetraspanin.
      
 0.507
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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