Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
S4R9U6_PETMAS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (282 aa)    
Predicted Functional Partners:
S4R810_PETMA
Uncharacterized protein.
    
 
 0.960
S4RA94_PETMA
Glyoxalase 1.
  
 
 0.831
S4RYJ6_PETMA
Sorbitol dehydrogenase.
  
 
 0.829
S4RAP0_PETMA
VOC domain-containing protein.
  
 
 0.735
S4RNJ4_PETMA
Glyoxalase domain containing 4.
  
 
 0.720
LIAS
Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
 
      0.624
S4R7Q7_PETMA
Glutamine amidotransferase like class 1 domain containing 3A.
      
 0.614
TPI1
Triosephosphate isomerase.
   
 
 0.611
S4RG23_PETMA
24-dehydrocholesterol reductase.
    
 0.608
S4RCJ6_PETMA
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
  
  
 0.604
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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