Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
S4RA93_PETMADNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (341 aa)    
Predicted Functional Partners:
RAD51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
    
 0.999
XRCC2
X-ray repair cross complementing 2.
   
 0.996
S4S079_PETMA
RAD51 paralog D.
    
 0.987
S4RPJ2_PETMA
RAD51 paralog B.
  
 
0.986
S4RX18_PETMA
Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily.
   
 0.983
S4RHC2_PETMA
RAD50 homolog, double strand break repair protein.
   
 0.976
S4R805_PETMA
MUS81 structure-specific endonuclease subunit.
   
 0.973
S4R5L5_PETMA
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
  
 0.970
S4RPK0_PETMA
Uncharacterized protein.
   
 0.956
S4RJK6_PETMA
Helicase C-terminal domain-containing protein.
  
 0.952
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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