Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
S4RAA2_PETMAUncharacterized protein. (258 aa)    
Predicted Functional Partners:
S4RYK6_PETMA
Ncstrn_small domain-containing protein.
   
 0.989
S4RRQ1_PETMA
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
   
 0.986
S4RAK4_PETMA
Presenilin enhancer, gamma-secretase subunit.
    
 0.985
S4RJ01_PETMA
APH1B gamma secretase subunit.
  
  
 
0.901
S4RLE7_PETMA
Uncharacterized protein.
  
  
 
0.901
S4RE56_PETMA
Uncharacterized protein.
     
  0.900
S4RAE8_PETMA
PNPLA domain-containing protein.
 
      0.661
S4RQF1_PETMA
Solute carrier family 25 member 20; Belongs to the mitochondrial carrier (TC 2.A.29) family.
 
    
 0.608
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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