Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
S4RAA5_PETMAMNAT1 component of CDK activating kinase. (238 aa)    
Predicted Functional Partners:
S4R5M3_PETMA
Cyclin_C_2 domain-containing protein.
   
 0.999
S4RK75_PETMA
Excision repair cross-complementation group 3.
    
 0.997
S4RQB2_PETMA
Excision repair cross-complementation group 2.
    
 0.996
S4RIB7_PETMA
General transcription factor IIH, polypeptide 3.
   
 0.992
S4RI17_PETMA
General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
    
 0.991
S4RSV8_PETMA
General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
    
 0.991
S4R8U4_PETMA
General transcription factor IIH, polypeptide 2.
   
 0.990
S4REK9_PETMA
Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
   
 0.990
S4R7M8_PETMA
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.988
S4RLL9_PETMA
General transcription factor IIE, polypeptide 1, alpha.
    
 0.985
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.