Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MARK3Non-specific serine/threonine protein kinase. (802 aa)    
Predicted Functional Partners:
S4RMW1_PETMA
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b; Belongs to the 14-3-3 family.
    
 0.783
S4RN92_PETMA
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
    
 0.744
S4RQ19_PETMA
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
    
 0.744
S4R574_PETMA
Phorbol-ester/DAG-type domain-containing protein.
    
 0.730
S4RSP4_PETMA
Serine/threonine kinase 11.
    
 0.671
S4R8K4_PETMA
Uncharacterized protein.
    
  0.634
S4RL04_PETMA
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family.
    
 0.634
S4RM58_PETMA
Protein kinase domain-containing protein.
    
  0.634
S4S0H9_PETMA
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family.
    
 0.634
S4RIG5_PETMA
HRas proto-oncogene, GTPase b.
    
  0.574
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
Server load: low (36%) [HD]