Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
S4RAH0_PETMAUncharacterized protein. (199 aa)    
Predicted Functional Partners:
S4R7V8_PETMA
Lysine (K)-specific demethylase 1a.
    
 0.978
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
    
  0.910
S4RMF1_PETMA
REST corepressor 1.
    
 0.909
S4RP19_PETMA
REST corepressor 1.
    
 0.909
S4RVB7_PETMA
REST corepressor 3.
    
 0.909
S4R8K9_PETMA
HDAC_interact domain-containing protein.
    
 
 0.868
S4RV40_PETMA
Hist_deacetyl domain-containing protein.
    
 0.806
S4RXT2_PETMA
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 0.806
S4R7I4_PETMA
Sin3A-associated protein.
    
  0.792
S4RFP2_PETMA
Uncharacterized protein.
    
  0.785
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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