STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
S4RCP9_PETMAPMS1 homolog 1, mismatch repair system component. (942 aa)    
Predicted Functional Partners:
S4R697_PETMA
MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).
  
 
0.996
S4RVU6_PETMA
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
 
 0.981
S4RJH0_PETMA
MutS homolog 2 (E. coli).
  
 0.979
S4RAF5_PETMA
MutS homolog 3 (E. coli).
 
 0.968
S4RQH3_PETMA
Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.
    
 0.940
S4RRM4_PETMA
Exonuclease 1.
   
 0.929
S4RTM7_PETMA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.875
RTEL1-TNFRSF6B
Helicase ATP-binding domain-containing protein.
   
 0.833
S4RVQ1_PETMA
HELICc2 domain-containing protein.
   
 0.833
S4RSI6_PETMA
PMS1 homolog 2, mismatch repair system component.
 
 
0.812
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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