STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (283 aa)    
Predicted Functional Partners:
S4RDE2_PETMA
Helicase ATP-binding domain-containing protein.
   
 0.995
S4REK3_PETMA
Helicase ATP-binding domain-containing protein.
   
 0.995
FANCM
Uncharacterized protein.
   
 0.995
S4RAE5_PETMA
Uncharacterized protein.
   
 0.994
S4RXX3_PETMA
Aspartyl-tRNA synthetase.
   
 0.940
S4R5L5_PETMA
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
    
 0.933
S4RJK6_PETMA
Helicase C-terminal domain-containing protein.
    
 0.899
S4RC13_PETMA
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.890
S4R805_PETMA
MUS81 structure-specific endonuclease subunit.
   
 0.889
S4RZP7_PETMA
Excision repair cross-complementation group 1.
   
 0.882
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.