Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MARCHF3RING-CH-type domain-containing protein. (196 aa)    
Predicted Functional Partners:
S4R5J2_PETMA
Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.615
S4R9B4_PETMA
Uncharacterized protein.
      
 0.505
S4R711_PETMA
Uncharacterized protein.
   
 
 0.503
S4R4C6_PETMA
Membrane-associated ring finger (C3HC4) 5.
   
  
 0.496
S4RB50_PETMA
CCR4-NOT transcription complex, subunit 2.
    
 
 0.492
S4RYG3_PETMA
NPL domain-containing protein.
    
 
 0.446
S4RSM9_PETMA
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
 0.431
S4RQ99_PETMA
NPL4 homolog, ubiquitin recognition factor.
    
 
 0.417
S4RRK1_PETMA
Ring finger protein 145b.
    
 
 0.415
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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