Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
S4RHC2_PETMARAD50 homolog, double strand break repair protein. (1041 aa)    
Predicted Functional Partners:
S4RG41_PETMA
FHA domain-containing protein.
   
 0.999
S4RPZ6_PETMA
MRE11 homolog A, double strand break repair nuclease.
  
 0.999
RAD51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
   
 0.998
S4RPL8_PETMA
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 0.997
S4RRM4_PETMA
Exonuclease 1.
  
 0.991
S4RZ01_PETMA
Uncharacterized protein.
    
 0.991
S4RKI1_PETMA
X-ray repair complementing defective repair in Chinese hamster cells 6.
   
 0.988
S4RDW5_PETMA
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 0.982
S4R5L5_PETMA
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
  
 0.981
S4RBC3_PETMA
Uncharacterized protein.
  
 0.980
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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