STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
S4RI17_PETMAGeneral transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (190 aa)    
Predicted Functional Partners:
S4RIB7_PETMA
General transcription factor IIH, polypeptide 3.
   
 0.993
S4R8U4_PETMA
General transcription factor IIH, polypeptide 2.
   
 0.990
S4R9F1_PETMA
General transcription factor IIH, polypeptide 5.
    
 0.988
S4RK75_PETMA
Excision repair cross-complementation group 3.
  
 0.985
S4RAA5_PETMA
MNAT1 component of CDK activating kinase.
    
 0.983
S4RQB2_PETMA
Excision repair cross-complementation group 2.
    
 0.983
S4RLL9_PETMA
General transcription factor IIE, polypeptide 1, alpha.
   
 0.982
S4R5M3_PETMA
Cyclin_C_2 domain-containing protein.
    
 0.979
S4RLK7_PETMA
Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.
    
 0.979
S4REK9_PETMA
Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
    
 0.974
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.