STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPMAP00000005166annotation not available (451 aa)    
Predicted Functional Partners:
S4REX2_PETMA
Annexin.
   
 0.780
PLA2G4A
Phospholipase A2, group IVAb (cytosolic, calcium-dependent).
    
 0.767
S4RFG4_PETMA
AP complex subunit beta.
    
  0.763
S4RDH8_PETMA
Enoyl-CoA delta isomerase 2.
    
  0.751
S4RRA2_PETMA
Enoyl-CoA delta isomerase 2.
    
  0.751
S4RY45_PETMA
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
  0.666
S4RVS6_PETMA
TNF receptor-associated factor 7.
    
 0.664
S4R738_PETMA
Uncharacterized protein.
    
 0.647
S4R496_PETMA
Adaptin_N domain-containing protein.
    
  0.644
S4RA77_PETMA
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
    
  0.644
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.