STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
S4RJN0_PETMASPO11 initiator of meiotic double stranded breaks. (190 aa)    
Predicted Functional Partners:
S4RB83_PETMA
WD repeat domain 61.
    
 
 0.918
S4RX18_PETMA
Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily.
    
 0.902
RAD51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
    
 0.854
S4R805_PETMA
MUS81 structure-specific endonuclease subunit.
    
 
 0.812
S4RDE2_PETMA
Helicase ATP-binding domain-containing protein.
    
 
 0.811
S4REK3_PETMA
Helicase ATP-binding domain-containing protein.
    
 
 0.811
FANCM
Uncharacterized protein.
    
 
 0.811
S4RA93_PETMA
DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.
    
 0.784
S4RKI4_PETMA
Apoptotic peptidase activating factor 1.
    
 
 0.779
S4RPZ6_PETMA
MRE11 homolog A, double strand break repair nuclease.
   
 0.773
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.