STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
S4RKD6_PETMAMicrotubule-associated protein 1 light chain 3 alpha. (121 aa)    
Predicted Functional Partners:
S4RTC7_PETMA
Uncharacterized protein.
   
 0.974
S4R4E8_PETMA
Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.
   
 0.966
S4RZB9_PETMA
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]
   
 0.958
S4RIB3_PETMA
Serine/threonine kinase 35.
   
 0.941
ATG14
Autophagy related 14.
   
 0.914
S4REM4_PETMA
Sequestosome 1.
   
 0.913
S4RZL6_PETMA
N_BRCA1_IG domain-containing protein.
    
 0.891
S4RYP8_PETMA
Zgc:73226.
   
 0.837
S4RKV5_PETMA
Beclin 1, autophagy related.
    
 0.806
S4RAR0_PETMA
Phosphatidylinositol 3-kinase, catalytic subunit type 3; Belongs to the PI3/PI4-kinase family.
    
 0.803
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.